Obviously designed to be used to cover textbooks, the set was clearly a 1968 issue as detailed on the box:
Looks like Topps had a promotional deal going on ("Sale-A-Bration") with this box, possibly indicative of poor sales.
The wrapper is, well, batty:
The checklist is handy but inaccurate:
No. 5 is listed as "Wacky Packages" but it ended up being something called "Topps Is What's Happening" presumably because of worries over potential legal issues with the former's intended subject:
(Courtesy The Sport Americana Price Guide to the Non-Sports Cards Number 4 by Chris Benjamin)
Intriguingly, you can see the baseball card depicted is a fair approximation of the burlapped 68's. No less than 13 Topps products are shown, including Bozo gumballs, which is helpful to me as I have been trying for ages to track when they went from bulk wholesale product to retail packaging. I like the checklist appearing on the product itself as well.
Here are a few others, it's a great (and very tough) set and the covers are quite fragile as these examples from an old Legendary auction show:
That looks like Paul Coker artwork on the left panel (UPDATE 11/11/23-It's not-Mark Newgarden advises it's in Art Spiegelman's hand) and I see Jack Davis's hand on the main part of the cover above. The whole set is peppered with art from MAD artists and it's amazing. Look at the ad section from the above example (click to blow it up):
Here is more Davis, look at this tableaux!
The left panel has the instructions and they are classic-check out no. 4:
Legendary also had a concept sketch from the set:
Topps had some great artwork early on (1950-51) but it's got nothing on their late 60's output.